Disease ⇒ Postmenopausal {40000277} Record Keys Type:Disease Parent:[ ] Definition:Postmenopausal Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:10051775 MedDra Level:pt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - #Estradiol-degrading #Klebsiella aerogenes from the feces of premenopausal females with #Depression > In mice, gavaging with this strain led to #Estradiol decline and #Depression-like behaviors. - The gene encoding the #Estradiol-degrading enzyme in K. aerogenes was identified as 3β-hydroxysteroid dehydrogenase (3β-HSD). - The prevalence of K. aerogene and 3β-HSD was higher in premenopausal women with #Depression than in those without #Depression. [1.2] [#Osteoporosis] [#humanized Galactooligosaccharides] - the prebiotic galactooligosaccharides (GOS) promotes the growth of #Bifidobacteria which increases calcium absorption and prevents bone loss and enhances calcium absorption and inhibits bone resorption in postmenopausal women - Gut #Bacteria that possess β-glucuronidase and/or β-galactosidase activity can metabolize #Estrogen including #Bifidobacterium, #Faecalibacterium, #Lactobacillus, #VeillonellaReferences Notes[ ]
