Disease ⇒ Hypercholesterolaemia {40000312}

Shared Reference Notes

• [1.1] 
  - coprostanol-forming microbes : ismA genes > cholesterol dehydrogenases : Cholestrol > contribute to coprostanol formation: significantly lower fecal cholesterol levels and lower serum total cholesterol with effects comparable to those attributed to variations in lipid homeostasis genes.
• [1.2] 
  - High levels of #Isobutyric acid could be one such biomarker for hypercholesterolemia.
• [1.3] [#Beta-glucan] [#Oat] 
  - Oats could be considered a functional food because of the presence of β-glucan, a soluble fiber shown to reduce #Cholesterol
• - #Bile Acids can be deconjugated by certain microbiota, which inhibits their reabsorption > elevation of bile acid synthesis inliver > reducing of Blood #Cholesterol
• [1.4] [#CVD] [#Enterococcus faecium, #Lactobacillus paracasei] [#Cholesterol] 
  - E. faecium strain 132 and L. paracasei strain 201 may alleviate hypercholesterolemia in rats
• - #Enterococcus faecium strain 132 and #Lactobacillus paracasei strain 201 reduced liver inflammation, improved the lipid profile by regulating the gene expression related to #Cholesterol metabolism and reduced fat accumulation.

References Notes