Probiotic (Bifidobacter and Lactobacilus) {50000117}

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Probiotic (Bifidobacter and Lactobacilus)
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Diet, Probiotic
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Shared Reference Notes

  • [1.1
    The probiotics improve ( Bifidobacterium (eg, B. longum, B. breve , and B. infantis ) and Lactobacillus (eg, L. helveticus , and L. rhamnosus ) psychiatric disorder-related behaviors including anxiety, depression, autism spectrum disorder (ASD), obsessive-compulsive disorder, and memory abilities, including spatial and non-spatial memory.
  • [1.2
    - The administration of a probiotic cocktail, composed of #Lactobacillus rhamnosus and #Lactobacillus helveticus, reduced the symptoms of #Depression and anxiety
  • [1.3
    - Certain probiotic bacteria reportedly demonstrated effects in suppressing and regressing #Cancer. - Their mechanisms include maintaining physicochemical conditions in the colon (e.g., pH and bile acid profile), balancing the quantity of beneficial gut microbiota members through the production of short-chain fatty acids, reducing the abundance of putrefactive bacteria producing enzymes such as azoreductase, β-glucosidase, β-glucuronidase, and nitroreductase, binding and degrading mutagenic compounds, as well as performing immunomodulatory activities. - Experimentations with wild-type probiotics have been performed against not only colorectal #Cancer, but also other cancers such as bladder, breast, cervical, and liver cancers. - Instead of oral administration, probiotics can also be delivered locally at tumor sites, which can reduce non-specific pharmacological effects on non-tumor tissues.
  • [1.4
    - Bacteria present in probiotics, particularly the common Lactobacillus and Bifidobacterium microbes, have been found to induce anti-#Cancer action by enhancing #Cancer cell apoptosis and protecting against oxidative stress. - Probiotics supplements also decrease the #Cancer-producing microorganism #Fusobacterium.
  • [1.5] [#Pregnancy
    - Probiotic supplementation > significantly reduced the severity of nausea, vomiting, constipation, and improved life quality in pregnant women. - Probiotic intake increased fecal bsh (bile salt hydrolase) > free #Bile Acids > facilitate intestinal mobility and metabolism > associated with lower vomiting scores.
  • [1.6
    -Lactobacillus salivarius and Bifidobacterium infantis >Transepithelial calcium transport >Enhanced intestinal calcium uptake
  • [1.7] [#Lactobacillus rhamnosus
    - #Probiotic > #Covid-19 > The proportion who developed symptoms was 26.4% with LGG versus 42.9% with placebo, a significant difference.
  • [1.8] [#Depression] [#Lactobacillaceae, #Limosilactobacillus (Lactobacillus) reuteri
    - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > reduction in depressive symptoms at four and eight weeks of treatment, and #Anxiety symptoms at four weeks. > improvement in #Sleep quality. - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > decrease in serum interleukin-6 levels. - Lactobacillus reuteri and #Bifidobacterium adolescentis Probitica > increased #Bifidobacteriaceae and Lactobacillacea, whereas it decreased #Enterobacteriaceae in the gut microbiota composition.
  • [1.9
  • [#Diabetic nephropathy] - Probiotics affected lipid metabolism parameters with decreasing triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) levels in patients with DKD. - Probiotics could also could improve inflammation and oxidative stress by decreasing high-sensitivity C-reactive protein (hs-CRP), plasma malondialdehyde (MDA), total antioxidant capacity (TAC), glutathione (GSH) and nitric oxide (NO).
  • [1.11] [#Probiotic
  • [1.12] [#CVD] [#Short Chain Fatty Acid] [#Probiotic
    - Short-chain fatty acids and secondary #Bile Acids can decrease #Cholesterol levels by regulating #Cholesterol metabolism. - Microbial #Bile Salt hydrolases can increase #Cholesterol disposal rates by accelerating its conversion to #Bile Acids. - Probiotics from the genera Lactobacillus and Bifidobacterium are efficient reducers of #Cholesterol levels in clinical studies. - Several candidate next-generation probiotics, including #Akkermansia muciniphila, #Bacteroides spp., #Clostridium spp., #Christensenella minuta, Eubacterium spp., and #Faecalibacterium prausnitzii, have been shown to decrease #Cholesterol levels in human or animal studies.
  • [1.13
    - Probiotic > boosting levels of Clostridia, Lachnospiracea and Akkermansia and increased levels of acetate, lactate, butyrate, isobutyrate, and propionate in the serum. However, only lactate and acetate were increased in the brain. - Probiotic > improved performance on the novel object recognition test, reduced brain damage, decreased Aβ plaques, increased SCFAs, and decreased plasma cytokine levels. - Bifidobacterium breve > reduced Aβ, Iba1, and pro-inflammatory cytokines, as well as increased ADAM10 and synaptic proteins. - Probiotics resulted in an improvement of cognition, a reduction in plasma malondialdehyde, a marker of oxidative stress, and a reduction in plasma CRP levels compared to controls

References Notes

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Common References

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