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Disease ⇒ Diabetic nephropathy {40000457}

Record Keys


Type:
Disease
Definition:
Diabetic nephropathy
Parent:[  ]

Details


Initialisation date:
2021-09-08
Other Terms:[  ]

Meta Information


MedDra ID:
10061835
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


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References Notes


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Shared Reference Notes


  • [1.2] [#Short Chain Fatty Acid
    - SCFA receptors are expressed in the kidneys, and emerging data have demonstrated that intestinal dysbiosis activates the renal renin-angiotensin system, which contributes to the development of DKD.
  • [1.3] [#Probiotic (Bifidobacter and Lactobacilus)
    - Probiotics affected lipid metabolism parameters with decreasing triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) levels in patients with DKD. - Probiotics could also could improve inflammation and oxidative stress by decreasing high-sensitivity C-reactive protein (hs-CRP), plasma malondialdehyde (MDA), total antioxidant capacity (TAC), glutathione (GSH) and nitric oxide (NO).