Disease ⇒ Diabetic nephropathy {40000457}
| Type: | Disease |
|---|---|
| Definition: | Diabetic nephropathy |
| Parent: | [ ] |
| Initialisation date: | 2021-09-08 |
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| Other Terms: | [ ] |
| MedDra ID: | 10061835 |
|---|---|
| MedDra Level: | pt |
| ICD: | [ ] |
| Category: | [ ] |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
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References Notes
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Shared Reference Notes
- [1.2] [#Short Chain Fatty Acid]
- SCFA receptors are expressed in the kidneys, and emerging data have demonstrated that intestinal dysbiosis activates the renal renin-angiotensin system, which contributes to the development of DKD. - [1.3] [#Probiotic (Bifidobacter and Lactobacilus)]
- Probiotics affected lipid metabolism parameters with decreasing triglycerides (TG), total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-c) levels in patients with DKD. - Probiotics could also could improve inflammation and oxidative stress by decreasing high-sensitivity C-reactive protein (hs-CRP), plasma malondialdehyde (MDA), total antioxidant capacity (TAC), glutathione (GSH) and nitric oxide (NO).