Disease ⇒ Allergy ⇒ Allergic rhinitis {40000130} Record Keys Type:Disease Parent:Allergy Definition:Allergic rhinitis Details Initialisation date:2021-03-02 Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:Immunology Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - Higher bacterial diversity may reduce the risk of allergic rhinitis later in childhood. [1.2] - The nasal microbiome of patients shows decreased heterogeneity and the increased abundance of one species, #Streptococcus salivarius. - This commensal bacterium contributes to AR development, promoting inflammatory cytokine release and morphological changes in the nasal epithelium that are characteristic of AR. [1.3] - #Parabacteroides had significantly higher relative abundances in the allergic rhinitis [1.4] - #Asthma, allergic rhinitis (or hay fever), #Food Allergy, and #Atopic Dermatitis (or eczema) can share many common etiological mechanisms characterized by aberrant type-2 inflammatory responses and elevated IgE [1.5] - butyrylated #Starch significantly increased the levels of colonic #Butyrate, and downregulated serum OVA-sIgE, IL-4, and IL-5, and improved symptoms in AR mice. In addition, the proportion of Treg cells in mesenteric lymph nodes and the levels of #IL-10 and TGF-β in the serum were elevated after butyrylated #Starch intervention. - butyrylated #Starch promoted the enrichment of beneficial genera in AR mice, such as #Lactobacillus, and alleviated the composition and structural disorder of gut microbiota in AR mice. References Notes[ ]
