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Disease ⇒ Tuberculosis {40000222}

Record Keys


Type:
Disease
Definition:
Tuberculosis
Parent:[  ]

Details


Initialisation date:[  ]
Other Terms:
TB

Meta Information


MedDra ID:
10044755
MedDra Level:
pt
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


[  ]

References Notes


[  ]

Shared Reference Notes


  • [1.3
    - The PTB group showed the most unique microbiota by higher abundance of Bifidobacteriaceae, Bifidobacteriales, Coriobacteriaceae, Coriobacteriales, Actinobacteria, Caulobacteraceae, Phyllobacteriaceae, Rhizobiales, Burkholderiaceae, Burkholderiaceae. Inflammatory status in PTB patients may be associated with the increased abundance of Clostridia and decreased abundance of Prevotella. We found that the abundance of Solobacterium and Actinobacteria was higher in the patients.
  • [1.5
    - Oral treatment of A. muciniphila or A. muciniphila-mediated palmitoleic acid strongly inhibits tuberculosis infection through epigenetic inhibition of tumour necrosis factor in mice infected with Mycobacterium tuberculosis.
  • - single-nucleotide polymorphism rs2257167 ‘G’ allele of type I interferon receptor 1 (encoded by IFNAR1 in humans) contributes to stronger type I interferon signalling, impaired colonization and abundance of A. muciniphila, reduced palmitoleic acid production, higher levels of tumour necrosis factor, and more severe tuberculosis disease in humans and transgenic mice
  • [1.6
    - Indole-3-propionic acid, an indole derivative, exhibits biological activities similar to those of indoles, such as affecting host susceptibility to Mycobacterium tuberculosis anticancer activity.