Thiamin [Vitamin B1] {90000165} Record Keys Parent:[ ] Definition:Thiamin Queue:Vitamin B1 Details Initialisation date:2021-05-10 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:Vitamin Function:[ ] Notes: [ ]Shared Reference Notes [1.1] - Increased abundances of #Alistipes senegalensis is associated to higher plasma levels of vitamin B1, which is produced by gut microbes. - A lack of vitamin B1 is known to affect the cardiovascular system and induce a fast heart rate [#Hypertension] [#Akkermansia muciniphila] - A. muciniphila > vitamin B1 productio > may influence blood pressure. [1.2] - more than 90% of other gut-associated #Bacteroides possess the ability for thiamin biosynthesis and the thiamin transporter genes - #Prevotella and #Desulfovibrio, is overexpressed with four enzymes—hydroxymethylpyridine kinase, phosphomethylpyridine kinase, thiamine-phosphate pyrophosphorylase, and thiamine-monophosphate kinase—crucial for thiamin biosynthesis - thiamine deficiency reduces the abundance of the Payer’s patches and decreases the size of B-cell follicles, leading to a reduction in naïve B cells in female Balb/c mice [1.3] [#Crohn’s disease] [#Candida albicans] [#Riboflavin] - Ca albicans is largely overrepresented in inflammatory (B1) vs stricturing (B2) phenotypes, and it is actually the only species showing significant differences. - An increased abundance of Ca albicans in inflammatory CD (B1) is consistent with its proinflammatory effects described in several studies.References Notes[ ]
