Disease ⇒ Allergy ⇒ Allergic asthma {40000349} Record Keys Type:Disease Parent:Allergy Definition:Allergic asthma Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:10001705 MedDra Level:llt ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - The gut bacteria byproduct p-cresol sulfate (PCS) produced via enhanced bacterial metabolism of the amino acid L-tyrosine and resultes in significant protective effects against allergic airway inflammation, [1.2] [#Asthma] [1.3] [#Acinetobacter lwoffii] [#Probiotic] - Repeated intranasal AL administration triggered a proinflammatory immune response particularly characterized by elevated levels of IL-6, and consequently, IL-6 induced IL-10 production in CD4+ T-cells. - Both IL-6 and IL-10, but not IL-17, were required for #Asthma protection.References Notes[ ]
