Methanobrevibacter ⇒ Methanobrevibacter smithii {10000180} Record Keys Parent:Methanobrevibacter Definition:Methanobrevibacter smithii Details Initialisation date:0000-00-00 LinksSource Meta Information Rank: Species Domain:Archaea Zone:[ ] Enzyme:[ ] Function:Mucin-degrading Notes: [ ]Shared Reference Notes [1.1] [#Obesity] [#Lactobacillus animalis] - several bacteria such as: Methanobrevibacter smithii, #Bifidobacterium spp., #Bifidobacterium animalis, #Escherichia coli, #Akkermansia muciniphila, #Anaerotruncus colihominis and bacteria of the Bacteroidetes strain have the capability to reduce the production of high-calorie substances and therefore also influence the caloric intake. A relatively low frequency of these bacteria correlates with increased body weight, as we have also observed. [1.2] - In a mouse model, it was demonstrated that Methanobrevibacter smithii, #Methanosarcina mazei, and #Methanomicrococcus blatticola use #TMA as growth substrates, resulting in reduced #Atherosclerosis [1.3] [#Pregnancy] - These metabolites were consistently associated with higher relative abundance of Methanobrevibacter smithii, which has been linked to improved energy harvest, obesity, impaired glucose tolerance, and diabetes [1.4] - Methanobrevibacter smithii is also significantly abundant in #Centenarians, but not in frail, elderly people. - Excesive #Sport > Methanobrevibacter Smithii (methane-producing bacteria) is also abundant; it is associated with an excessive production of energy and carbohydrate metabolism . [1.5] [#Alzheimer’s disease] [#Short Chain Fatty Acid] - Methanobrevibacter smithii was associated with preclinical AD and was negatively correlated with fecal concentrations of #Butyrate, a SCFA that attenuated Aβ plaque deposition and neuroinflammation in a mouse model of AD. [1.6] [#Multiple Sclerosis] - Ms > The clinically active group showed significant enrichment of Methanobrevibacter smithii and #Victivallis vadensis.References Notes[ ]
