Pseudomonadaceae ⇒ Faecalibaculum rodentium {10000169}
Parent: | |
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Definition: | Faecalibaculum rodentium |
Initialisation date: | 0000-00-00 |
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Rank: | Genus |
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Domain: | Bacteria |
Zone: | [ ] |
Enzyme: | [ ] |
Function: | Anti-cancer |
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Shared Reference Notes
- [1.1] [#Breast cancer] [#Antibiotic Therapy]
- Antibiotic-induced perturbation of the gut microbiota > increases tumor progression in multiple BrCa mouse models > increased number of cells with a stromal signature in tumors > increased abundance of mast cells in the tumor stromal regions. - Re-supplementation of antibiotic-treated mice with Faecalibaculum rodentium > restored tumor growth to control levels - Mast cell stabilizer, #Cromolyn > decreases tumor growth only in antibiotic treated animals - [1.2] [#Prediabetes] [#High Fat Diet]
- microbiota protects against development of #Obesity, #Metabolic syndrome, and pre-diabetic phenotypes by inducing commensal-specific Th17 cells. - High-fat, high-#Sugar diet promoted metabolic disease by depleting Th17-inducing microbes, and recovery of commensal Th17 cells restored protection. - Diet-induced loss of protective Th17 cells was mediated by the presence of #Sugar. - Eliminating #Sugar from high-fat diets protected mice from #Obesity and #Metabolic syndrome in a manner dependent on commensal-specific Th17 cells. - #Sugar and ILC3 promoted outgrowth of Faecalibaculum rodentium that displaced Th17-inducing microbiota. - [1.3] [#Amedibacterium Intestinale]
- #Agavins (AG), either alone or combined with cranberry #Polyphenols (CP+AG), mainly stimulated the glycan-degrading bacteria Muribaculum intestinale, Faecalibaculum rodentium, #Bacteroides uniformis, and #Bacteroides acidifaciens. - This increase of glycan-degrading bacteria was consistent with a significantly increased level of #Butyrate in obese mice receiving AG, - [1.4]
- Several species of Bacteroides and Parasutterella were previously shown to be capable of restoring antitumor responses such as #Bacteroides thetaiotaomicron, #Bacteroides rodentium, and #Parasutterella excrementihominis
References Notes
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