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Paenibacillus ⇒ Paenibacillaceae {10001171}

Record Keys


Organism:
Paenibacillus
Parent:

Details


Initialisation date:[  ]

Meta Information


Rank:
 Genus
Domain:
 Bacteria
Zone:[  ]
Enzyme:[  ]
Function:[  ]

Notes:


[  ]

References Notes


[  ]

Shared Reference Notes


  • [1.4
    - gut microbe–derived metabolite trimethylamine N-oxide (#TMAO), enhanced antitumor immunity to Pancreatic ductal adenocarcinoma (PDAC) - Delivery of #TMAO intraperitoneally or via a dietary choline supplement to orthotopic PDAC-bearing mice reduced tumor growth, associated with an immunostimulatory tumor-associated macrophage (TAM) phenotype, and activated effector T cell response in the tumor microenvironment. - #TMAO potentiated the type I interferon (IFN) pathway and conferred antitumor effects in a type I IFN–dependent manner. - bacteria producing an enzyme that generates #TMA was associated with positive immunotherapy outcomes in people with #Pancreatic Cancer. - #Bacillus and Paenibacillus species, were present at higher levels in people who survived for a long period of time after #Pancreatic Cancer.