Pancreatic polypeptide YY {90000533} Record Keys Parent:[ ] Definition:Pancreatic polypeptide YY Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Obesity] [#Short Chain Fatty Acid] - SCFAs act as signalling molecules, activating the free fatty acid receptors, increasing #Leptin, GLP-1, and PYY, promoting satiety. [1.2] - Paneth cells in the gut secrete several #Antimicrobial peptides into the lumen to regulate the microbiota, as well as pancreatic polypeptide YY (PYY). - The Paneth cell–derived PYY was full length, unlike the endocrine form, and although it had some antibacterial activity, it was most effective at inhibiting the ubiquitous gut fungus #Candida albicans from transforming from the commensal yeast form into the invasive hyphal form ( against virulent #Candida albicans hyphae—but not the yeast form). [1.3] [#Short Chain Fatty Acid] - SCFA production is associated with the synthesis and secretion of intestinal hormones, such as GLP-1 and PYY, which play a role in satiety, intestinal transit, and homeostasisReferences Notes[ ]
