Disease ⇒ Hypertension ⇒ Gestational Hypertension {40000184}

Record Keys


Type:
Disease
Parent:
Definition:
Gestational Hypertension

Details


Initialisation date:
2020-10-04
Other Terms:[  ]

Meta Information


MedDra ID:[  ]
MedDra Level:[  ]
ICD:[  ]
Category:
Cardiovascular, Obstetrics
Zone:[  ]
Mechanism:[  ]

Notes:


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Shared Reference Notes


  • [1.1] [#Hypertension
    - #Bacillus was associated with high blood pressure
  • [#Hypertension] - a negative association between #Shewanella and Diastolic BP. - #Shewanella, commonly known as an environmental bacteria, has recently been reported to play an important role in multiple drug resistances
  • [#Preeclamsia] - the relative abundance of #Methanobrevibacter is higher in healthy controls than in HDP cases during both early and late pregnancies.
  • - It is not the composition of the whole GM, but maybe some certain taxa that change during #Pregnancy and have effects on HDP.
  • - the relative abundance of #Polycyclovorans and #Pelomonas in GH / PE in early #Pregnancy was significantly higher than that in healthy control, and these bacteria were also enriched in the late trimester of GH / PE patients.
  • [1.2
    - The abundance of the butyrate-producing genus Odoribacter was inversely correlated with systolic blood pressure. - In obese pregnant women, butyrate production capacity is decreased, but plasminogen activator inhibitor-1 concentrations increased. - Plasminogen activator inhibitor-1 levels were inversely correlated with expression of butyrate kinase and Odoribacter abundance. - In overweight and obese pregnant women at 16 weeks gestation, the abundance of butyrate-producing bacteria and butyrate production in the gut microbiota is significantly negatively associated with blood pressure and with plasminogen activator inhibitor-1 levels.

References Notes


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