Stearate {90000672}

Record Keys
Parent:[  ]
Definition:
Stearate
Queue:[  ]

Details
Initialisation date:[  ]
Specification:
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Source:
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Meta Information
Structural Type:
Fatty acid
Functional Type:
Energy Source
Function:[  ]

Notes:

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Shared Reference Notes

  • [1.1] 
    - Numerous animal and plant fats contain stearate, an 18-carbon saturated fatty acid. Stearate is crucial for the growth of different tumors because it alters mitochondrial morphology, rendering #Cancer cells vulnerable to #Oxidative stress and cell death
  • [#Irritable bowel syndrome] - Stearates are also associated with intestinal permeability, which may explain their causal association with IBS.
  • - stearate, a saturated fatty acid, serves as an agonist of Toll-like receptor 4, initiating an inflammatory response and leading to alterations in the gut microbiota.
  • [1.2] [#Irritable bowel syndrome] [#Myristic acid] 
    - elevated concentrations of #Butyryl carnitine and tetradecanedioate are associated with heightened vulnerability to IBS, while increasing levels of stearate (18:0) exhibit a protective effect. - stearate (18:0), #Butyryl carnitine and tetradecanedioate can directly affect IBS independently of other metabolites.

References Notes

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