Olopatadine {90000325} Record Keys Parent:[ ] Definition:Olopatadine Queue:[ ] Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:Anti-inflammatory Notes: [ ]Shared Reference Notes [1.1] [#Systemic lupus erythematosus] - The SLE-enriched genera, including Bacteroides, were positively correlated with several SLE-enriched metabolites, including olopatadine. - The SLE-depleted genera, such as Pseudomonas, were negatively correlated to SLE-depleted cytokines, including interleukin-8. - Megamonas and Phocaeicola were negatively correlated with serum complement component 3, and Streptococcus was positively correlated with IgG. [#Systemic lupus erythematosus] - Olopatadine, were more abundant in SLE patients. Olopatadine appears to have significant anti-inflammatory activity, and inhibits histamine release from mast cells. Thus, the increase of olopatadine in urine might play a potential protective role for SLE patients.References Notes[ ]
