Cytolethal Distending Toxin {90000197} Record Keys Parent:[ ] Definition:Cytolethal Distending Toxin Queue:[ ] Details Initialisation date:2021-09-11 Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:Oncogenesis, Genotoxin Notes: [ ]Shared Reference Notes [1.1] [#Cancer] - Cytolethal Distending Toxin (CDT) by #Campylobacter jejuni and Colibactin by Escherichia Coli can directly damage DNA [1.2] [#Colorectal cancer] - #Campylobacter jejuni, was found to promote the growth and enlargement of colorectal tumors in mice, and induces changes in microbial composition and transcriptomic responses, a process dependent on cytolethal distending toxin (CDT) productionReferences Notes[ ]
