Disease ⇒ Immunotherapy-induced colitis {40000144}
| Type: | Disease |
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| Parent: | [ ] |
| Definition: | Immunotherapy-induced colitis |
| Initialisation date: | 0000-00-00 |
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| Other Terms: | [ ] |
| MedDra ID: | [ ] |
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| MedDra Level: | [ ] |
| ICD: | [ ] |
| Category: | [ ] |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
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Shared Reference Notes
- [1.1]
- Dietary prebiotics, which can be metabolized by bacteria to produce #Butyrate, can be an intriguing new investigational approach to prevent immunotherapy-induced colitis and lead to improved patient outcomes. - #Butyrate is a gut-microbiome-derived, anti-inflammatory metabolite that could be protective against ICI colitis, based on data from other forms of colitis. - #Dietary prebiotic starches that can increase #Butyrate production are a promising method of microbial manipulation that could be used to mitigate ICI colitis.
References Notes
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