MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Salmonella typhimurium ⇒ Salmonella {10000155}

Record Keys


Organism:
Salmonella typhimurium
Parent:

Details


Authoring date:
2020-09-06

Links


Meta Information


Taxonomy:
Species
Domain:
Bacteria
Zone:[  ]
Enzyme:[  ]
Function:[  ]

Notes


[  ]

Shared Notes


  • [1.1
    - S. typhimurium, an intracellular pathogen, is chemoattracted to, and retained in, tumors due to the presence of metabolites produced by quiescent cancer cells within the TME (Tumor Micro envirounment).
    - Once in the tumor, S. typhimurium continues to proliferate and directly kills cancer cells by triggering of apoptosis, necrosis, and cell rupture.
    - S. typhimurium flagellin has been found to mount the antitumor response of CD8+ T and Natural Killer (NK) cells and to reduce the frequency of regulatory T cells (Tregs)

Common References