MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Roseburia {10000139}

Record Keys


Organism:
Roseburia
Class:[  ]

Details


Initialisation date:
2019-08-11

Links


Meta Information


Taxonomy:
Genus
Domain:
Bacteria
Zone:[  ]
Enzyme:[  ]
Function:
Anti-inflammatory

Notes


[  ]

Shared Notes


  • [1.115
    - Roseburia, was found to be reduced in IBD.
    - It had the highest correlations occurring in a number of bile acids (e.g., taurocholate, taurochenodeoxycholate, glycocholate), in addition to several triacylglycerols (TAGs) and fatty acids.
    - Specifically, the short chain fatty acid (SCFA) butyrate was found to be positively associated with Roseburia abundance, consistent with known butyrate production in the Roseburia genus.
    - Roseburia has a known anti-inflammatory role in the intestine and it’s positive association with butyrate is consistent with a deficiency in this genus being highly predictive of IBD.
  • [1.116
    - Other butyrate producing microbes, e.g. Roseburia spp., fare better when they are delivered polysaccharide growth substrates in the diet
  • [1.117
    - SFAs were positively associated with Roseburia, a biomarker for the lean group.

Common References