Faecalibacterium prausnitzii ⇒ Faecalibacterium {10000130}
Organism: | Faecalibacterium prausnitzii |
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Parent: |
Authoring date: | 2020-09-06 |
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Taxonomy: | Species |
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Domain: | Bacteria |
Zone: | Gut Lumen |
Enzyme: | [ ] |
Function: | Anti-inflammatory |
Notes
- F. prausnitziiis the largest producer of butyrate and the largest consumer of acetate and is the most important species inhabiting the intestine. Its depletion along with the reduction of Bifidobacterium (which is more reduced in patients with kidney stones) leads to a reduction in the intestinal butyrate levels, which thence leads to a functional instability in the gastrointestinal tract and urothelium thereby resulting in an inflammatory pattern. (1)
-These bacteria, which are often diminished in patients with Crohn's disease, appear to exert many of their protective effects through the release of a fatty acid called butyrate.
Common References
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- [1.64] Structural and functional characterization of the gut microbiota in elderly women with migraine [2020] [80001365] [Frontiers in Cellular and Infection Microbiology]
- [1.65] Dysbiosis in the gut microbiota of patients with multiple sclerosis, with a striking depletion of species belonging to Clostridia XIVa and IV clusters. [2015] [80000233] [PLOS ONE]
- [1.66] Altered gut microbiota in myasthenia gravis [2018] [80000850] [Frontiers in Microbiology]
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- [1.68] A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease [2019] [80000948] [Nature communications]
- [1.69] Altered intestinal microbiota in patients with chronic pancreatitis: implications in diabetes and metabolic abnormalities [2017] [80000567] [Scientific Reports]
- [1.70] Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls [2016] [80000274] [Parkinsonism and Related Disorders]
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- [1.72] Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis [2014] [80000461] [Arthritis Research & Therapy]
- [1.73] Disordered intestinal microbes are associated with the activity of systemic lupus erythematosus [2019] [80000934] [Clinical Sciences ]
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- [1.75] Gut microbiota imbalances in Tunisian participants with type 1 and type 2 diabetes mellitus [2019] [80001121] [Bioscience Reports]
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- [1.78] Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss [2010] [80001231] [Diabetes]
- [1.79] A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis [2014] [80000592] [Gut]
- [1.80] Gut microbiota differs between children with inflammatory bowel disease and healthy siblings in taxonomic and functional composition: a metagenomic analysis [2017] [80000660] [American journal of physiology. Gastrointestinal and liver physiology]