Citrobacter rodentium ⇒ Citrobacter {10000222}
| Organism: | Citrobacter rodentium |
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| Class: |
| Initialisation date: | 2019-08-10 |
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| Taxonomy: | Species |
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| Domain: | Bacteria |
| Zone: | [ ] |
| Enzyme: | [ ] |
| Function: | [ ] |
Notes
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Shared Notes
- [1.3]
- Switching mice from a standard grain-based rodent chow to a high-fat, low-fiber Western-style diet resulted in a rapid reduction in the number of gut bacteria.
- Mice fed the Western-style diet were frequently unable to clear the pathogen Citrobacter rodentium from the colon. They were also prone to developing chronic infection when re-challenged by this pathogen. - [1.2]
- Pectins > anti-inflammatory properties on intestinal immunity > direct interactions on Toll-like receptors (TLRs) in the small intestine or via stimulating microbiota-dependent effects in the large intestine.
- Pectins> prevent C. rodentium induced colonic inflammation > lowering the C. rodentium load in the caecum independently of the DB.
Common References
- [1.1] Intestinal infection triggers Parkinson’s disease-like symptoms in Pink1−/− mice [2019] [Abstract] [Nature] [Journal] [80001630]
- [1.2] Pectins that Structurally Differ in the Distribution of Methyl‐Esters Attenuate Citrobacter rodentium‐Induced Colitis [2021] [Molecular Nutrition & Food Research] [Journal] [80002097]
- [1.3] Western-style diet impedes colonization and clearance of Citrobacter rodentium [2021] [Research] [PLOS Pathogens] [Journal] [80001807]