Glycolipid ⇒ 3-sulfogalactosyl diacylglycerols [SGDG] {90000359} Record Keys Parent:Glycolipid Definition:3-sulfogalactosyl diacylglycerols Queue:SGDG Details Initialisation date:[ ] Specification: [ ]Source: [ ] Meta Information Structural Type:[ ] Functional Type:[ ] Function:Immun regulator, Anti-inflammatory, Immunosuppressive Notes: [ ]Shared Reference Notes [1.1] [#Aging] - 3-sulfogalactosyl diacylglycerols (SGDGs) and SGDG pathway members, including the potential degradation products lyso-SGDGs. SGDGs show an age-related decline specifically in the central nervous system and are associated with myelination. - SGDG dramatically suppresses LPS-induced gene expression and release of pro-inflammatory cytokines from macrophages and microglia by acting on the NF-κB pathway.References Notes[ ]
