Trichloroethylene {90000150} Record Keys Parent:[ ] Definition:Trichloroethylene Queue:[ ] Details Initialisation date:2021-04-11 Specification: TCESource: [ ] LinksInfolink Meta Information Structural Type:[ ] Functional Type:[ ] Function:[ ] Notes: [ ]Shared Reference Notes [1.1] [#Parkinson’s Disease] - Trichloroethylene (TCE) is an environmental contaminant and Parkinson’s risk factor. - Chronic TCE treatment in rats caused dopaminergic neurodegeneration. - TCE exposure elevated LRRK2 kinase activity in the nigrostriatal tract and causes dopaminergic pathology, endolysosomal dysfunction, protein accumulation.References Notes[ ]
