Microbiome & Chronic Diseases

Evidence Based Medicine

Bipolar disorder {40000198}

Record Keys
Definition:	Bipolar disorder
Class:	[ ]

Details
Other Terms:	[ ]
Authoring date:	[ ]

Meta Information
ICD:	[ ]
Category:	[ ]
MedDra ID:	10057667
MedDra Level:	pt

Notes

[ ]

Shared Notes

[1.7]
- Family Ruminococcaceae, genus Faecalibacterium, and species Faecalibacterium prausnitzii. Members of this clade, known for butyrate production, are reduced in BD.
[1.8]
- In bipolar disorder, gut microbiota alpha-diversity decreased with increasing illness duration.
- In bipolar disorder, Actinobacteria and Coriobacteria were overrepresented in patients compared to healthy controls

Common References

[1.1] Gut microbiota changes in patients with bipolar depression [2019] [80001106] [Advanced Science] [Journal]
[1.2] Characterizing the gut microbiota in adults with bipolar disorder: a pilot study [2019] [80001188] [Nutritional Neuroscience] [Journal]
[1.3] A step ahead: exploring the gut microbiota in inpatients with bipolar disorder during a depressive episode [2019] [80001119] [Bipolar Disorders] [Journal]
[1.4] The gut microbiome composition associates with bipolar disorder and illness severity [2017] [80000266] [Journal of Psychiatric Research] [Journal]
[1.5] Gut microbiota composition in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives [2019] [80001072] [Brain, Behavior, and Immunity] [Journal]
[1.6] Gut microbial signatures can discriminate unipolar from bipolar depression [2020] [80001346] [Advanced Science] [Journal]
[1.7] Bipolar Disorder and the Gut Microbiome: a Systematic Review [2021] [Review] [80001607] [Bipolar Disorders] [Journal]
[1.8] The Role of Gut Microbiota in the High-Risk Construct of Severe Mental Disorders: A Mini Review [2021] [Review] [80001729] [Frontiers in Psychiatry] [Journal]

Increased abundance of

‐ Bacteroides Faeces ‎Human [1.1]
‐ Clostridiaceae Faeces ‎Human [1.2]
‐ Coriobacteriaceae Faeces ‎Human [1.3]
‐ Faecalibacterium Faeces ‎Human [1.4]
‐ Flavonifractor Faeces ‎Human [1.5, 1.5]
‐ Halomonas Faeces ‎Human [1.1]
‐ Parabacteroides Faeces ‎Human [1.1]
‐ Proteobacteria Faeces ‎Human [1.6]
‐ Pseudomonadaceae Faeces ‎Human [1.6]
‐ Weissella Faeces ‎Human [1.1]

Decreased abundance of

‐ Bacteroidetes Faeces ‎Human [1.6]
‐ Coprococcus Faeces ‎Human [1.1]
‐ Faecalibacterium Faeces ‎Human [1.1, 1.3]
‐ Gemmiger Faeces ‎Human [1.1]
‐ Parasutterella Faeces ‎Human [1.1]
‐ Roseburia Faeces ‎Human [1.1]
‐ Ruminococcaceae Faeces ‎Human [1.3]
‐ Ruminococcus Faeces ‎Human [1.1]