Chronic Rhinosinusitis {40000196}

Record Keys
Definition:	Chronic Rhinosinusitis
Class:	[ ]

Details
Other Terms:	CRS
Initialisation date:	[ ]

Meta Information
ICD:	[ ]
Category:	[ ]
MedDra ID:	10071399
MedDra Level:	pt

Notes

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Shared Notes

[1.9]
- The healthy people had up to 10 times more Lactobacilli in some parts of their noses in comparision to patients suffering froM Chronic Rhinosinusitis.
- Lactic acid bacteria are enriched in the healthy human nose and nasopharynx
- Lactobacillus casei AMBR2 is functionally adapted to the upper respiratory tract
- L. casei AMBR2 has antimicrobial and immunomodulatory properties
- Live L. casei AMBR2 is safe for intranasal application in healthy humans

Common References

[1.1] Impact of cigarette smoking on the middle meatus microbiome in health and chronic rhinosinusitis [2015] [International forum of allergy & rhinology] [Journal] [80000887]
[1.2] Nasal Airway Microbiota Profile and Severe Bronchiolitis in Infants: A Case-Control Study [2016] [The Pediatric infectious disease journal] [Journal] [80000439]
[1.3] The microbiome of chronic rhinosinusitis: culture, molecular diagnostics and biofilm detection. [2013] [BMC Infectious Diseases] [Journal] [80000440]
[1.4] Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis. [2012] [Science translational medicine] [Journal] [80000251]
[1.5] Chronic Rhinosinusitis: Potential role of microbial dysbiosis and recommendation for sampling sites [2018] [Frontiers in Cellular and Infection Microbiology] [Journal] [80000700]
[1.6] Decreased diversity of nasal microbiota and their secreted extracellular vesicles in patients with chronic rhinosinusitis based on a metagenomic analysis [2014] [Allergy] [Journal] [80000559]
[1.7] Microbiology of middle meatus in chronic rhinosinusitis [2007] [Brazilian Journal of Otorhinolaryngology] [Journal] [80000394]
[1.8] The sinonasal microbiota, neural signaling, and depression in chronic rhinosinusitis [2018] [International forum of allergy & rhinology] [Journal] [80000717]
[1.9] Lactobacilli Have a Niche in the Human Nose [2021] [Research] [Cell Reports] [Journal] [80001688]
[1.10] Sinus microbiota varies among chronic rhinosinusitis phenotypes and predicts surgical outcome [2015] [Journal of Allergy and Clinical Immunology] [Journal] [80000512]

Increased abundance of

‐ Campylobacter Swab left and right middle meatus ‎Human [1.1]
‐ Corynebacterium accolens Sinus lavage ‎Human [1.2]
‐ Corynebacterium pseudodiphtheriticum Tissue biopsie ‎Human [1.3]
‐ Corynebacterium tuberculostearicum Sinus brush ‎Human [1.4]
‐ Curtobacterium Sinus lavage ‎Human [1.2]
‐ Escherichia Swab left and right middle meatus ‎Human [1.5]
‐ Fusobacterium Swab left and right middle meatus ‎Human [1.1]
‐ Haemophilus influenzae Tissue biopsie ‎Human [1.3]
‐ Lactobacillus casei ‎Ameliorative ‎Nasopharynx ‎Human
‐ Moraxella catarrhalis Tissue biopsie ‎Human [1.3]
‐ Nocardia asteroides Tissue biopsie ‎Human [1.3]
‐ Prevotella dentalis Sinus lavage ‎Human [1.2]
‐ Pseudomonas aeruginosa Sinus lavage ‎Human [1.2]
‐ Pseudomonas aeruginosa Tissue biopsie ‎Human [1.3]
‐ Pseudomonas Sinus lavage ‎Human [1.2]
‐ Staphylococcus aureus Nasal lavage ‎Human [1.6]
‐ Staphylococcus aureus Sinus lavage ‎Human [1.2]
‐ Staphylococcus aureus Tissue biopsie ‎Human [1.3]
‐ Streptococcus pneumoniae Nasal swab ‎Human [1.7]
‐ Streptococcus pneumoniae Tissue biopsie ‎Human [1.3]

Decreased abundance of

‐ Alicycliphilus Sinus lavage ‎Human [1.2]
‐ Anaerococcus Tissue biopsie ‎Human [1.8]
‐ Bacteroides Swab left and right middle meatus ‎Human [1.1]
‐ Bacteroidetes Nasal lavage ‎Human [1.6]
‐ Carnobacterium alterfunditum Sinus brush ‎Human [1.4]
‐ Cloacibacterium Sinus lavage ‎Human [1.2]
‐ Clostridiales Swab left and right middle meatus ‎Human [1.1]
‐ Enterococcus mundtii Sinus brush ‎Human [1.4]
‐ Lachnospiraceae Swab left and right middle meatus ‎Human [1.1]
‐ Lactobacillus sakei Sinus brush ‎Human [1.4]
‐ Lactobacillus ‎Causal ‎Nasopharynx ‎Human [1.9]
‐ Oxalobacteraceae Swab left and right middle meatus ‎Human [1.1]
‐ Parabacteroides Swab left and right middle meatus ‎Human [1.1]
‐ Pediococcus pentosaceus Sinus brush ‎Human [1.4]
‐ Peptoniphilus Nasal swab ‎Human [1.10]
‐ Propionibacterium acnes Tissue biopsie ‎Human [1.3]
‐ Propionibacterium Nasal swab ‎Human [1.10]
‐ Ruminococcaceae Swab left and right middle meatus ‎Human [1.1]
‐ Staphylococcus aureus Nasal swab ‎Human [1.7]
‐ Staphylococcus epidermidis Tissue biopsie ‎Human [1.3]
‐ Streptococcus agalactiae Tissue biopsie ‎Human [1.3]

Related Factor

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References

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Chronic Rhinosinusitis {40000196}

Record Keys

Details

Meta Information

Notes

Shared Notes

Common References