MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Gestational Hypertension ⇒ Hypertension {40000184}

Record Keys
Definition:
Gestational Hypertension
Class:

Details
Other Terms:[  ]
Initialisation date:
2020-10-04

Meta Information
ICD:[  ]
Category:
Cardiovascular, Obstetrics
MedDra ID:[  ]
MedDra Level:[  ]

Notes

[  ]

Shared Notes

  • [1.1] 
    - The abundance of the butyrate-producing genus Odoribacter was inversely correlated with systolic blood pressure.
    - In obese pregnant women, butyrate production capacity is decreased, but plasminogen activator inhibitor-1 concentrations increased.
    - Plasminogen activator inhibitor-1 levels were inversely correlated with expression of butyrate kinase and Odoribacter abundance.
    - In overweight and obese pregnant women at 16 weeks gestation, the abundance of butyrate-producing bacteria and butyrate production in the gut microbiota is significantly negatively associated with blood pressure and with plasminogen activator inhibitor-1 levels.

Common References