Disease ⇒ Fibromyalgia {40000178}
| Type: | Disease |
|---|---|
| Definition: | Fibromyalgia |
| Parent: | [ ] |
| Initialisation date: | 2020-09-06 |
|---|---|
| Other Terms: | Complex Regional Pain Syndrome, CRPS, Myofascial Pain Syndrome |
| MedDra ID: | 10048439 |
|---|---|
| MedDra Level: | pt |
| ICD: | [ ] |
| Category: | Musculoskeletal, Rheumatology |
| Zone: | [ ] |
| Mechanism: | [ ] |
Notes:
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References Notes
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Shared Reference Notes
- [1.1]
- Chronic fatigue syndrome (CFS) shares some symptomatic features with FM. - [1.3]
- Alterations in the relative abundance of several bacterial species known to metabolize bile acids were observed in women with fibromyalgia, accompanied by significant alterations in the serum concentration of #Secondary bile acids, including a marked depletion of #α-muricholic acid. - Serum #α-muricholic acid was highly correlated with symptom severity, including pain intensity and fatigue. - [1.5] [#Chronic Musculoskeletal Pain, #Vitamin D deficiency, #Vitamin D deficiency-mediated chronic pain]
- 25OHD supplementation results in pain reduction. Our results suggest a possible role of #Vitamin D supplementation in alleviating the pain associated with FMS and CMP, especially in #Vitamin D-deficient individuals.