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Microbiome & Chronic Diseases

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Disease ⇒ Critically ill conditions {40000168}

Record Keys


Type:
Disease
Definition:
Critically ill conditions
Parent:[  ]

Details


Initialisation date:
2021-09-13
Other Terms:[  ]

Meta Information


MedDra ID:[  ]
MedDra Level:[  ]
ICD:[  ]
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Notes:


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References Notes


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Shared Reference Notes


  • [1.1
    - The critical ill patients had about 10,000 times lower total anaerobes, including Bifidobacterium and Lactobacillus, and 100 times higher Staphylococcus.
    - Total organic acids, acetic acid, and especially butyric acid derived from gut microbiota are significantly decreased.
    - The gut microbiota begins to change within the first 6 h.
    - 17 species of bacteria, including Clostridiales, induce regulatory T cells.
    - ICU patients are significantly lower in the proportions of the class Clostridia.
    - IFN-γ-producing CD8 + cells were induced by 11 species of bacteria included in the phyla Bacteroidetes, Firmicutes, and Fusobacterium.