Urinary stone disease {40000161}
| Definition: | Urinary stone disease |
|---|---|
| Class: | [ ] |
| Other Terms: | Urinary Calculi, Nephrolithiasis, Stones, Urolithiasis |
|---|---|
| Authoring date: | 2020-09-06 |
| ICD: | [ ] |
|---|---|
| Category: | Renal |
| MedDra ID: | [ ] |
| MedDra Level: | [ ] |
Notes
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Shared Notes
- [1.1]
- Lactobacillus may inhibit stone growth. However, our multi-omics integration strongly points to three unknown metabolites.
- The bacterium Oxalobacter formigenes uses oxalate as a carbon and energy source for growth, is negatively associated with both USD and urinary oxalate, is sensitive to common antibiotics, and can reduce urinary oxalate when administered orally as a probiotic, all of which implicates loss of function dysbiosis associated with this species and calcium oxalate stone formation.
Common References
- [1.1] Defining Dysbiosis in Patients with Urolithiasis [2019] [Research] [80000044] [Scientific Reports]