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Disease ⇒ Glioblastoma {40000155}

Record Keys


Type:
Disease
Definition:
Glioblastoma
Parent:[  ]

Details


Initialisation date:
2021-06-16
Other Terms:[  ]

Meta Information


MedDra ID:[  ]
MedDra Level:[  ]
ICD:[  ]
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Notes:


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References Notes


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Shared Reference Notes


  • [1.1
    - This is the first report of confirmed IDH1-mutant GBM treated with KMT and surgical debulking without chemo- or radiotherapy. The long-term survival of this patient, now at 80 months, could be due in part to a therapeutic metabolic synergy between KMT and the IDH1 mutation that simultaneously target the glycolysis and glutaminolysis pathways that are essential for GBM growth.