MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Non-alcoholic fatty liver disease ⇒ Steatohepatitis {40000151}

Record Keys
Definition:
Non-alcoholic fatty liver disease
Class:

Details
Other Terms:
NAFLD, NAFLD, Nonalcoholic Steatohepatitis, NASH
Initialisation date:
2020-09-06

Links

Meta Information
ICD:[  ]
Category:
Gastroenterology
MedDra ID:
10082249
MedDra Level:
pt

Notes

- Low levels of Parabacteroides distasonis lead to the development of NASH and increase cardiovascular risk. (1)
- Decreased levels of Prevotella might be detrimental for adults with NAFLD. (2)

Shared Notes

  • [1.16] 
    - Metagenome-based gut microbiome panel can accurately diagnose advanced fibrosis
  • [1.7] 
    - Butyrate-producing bacteria were decreased and ethanol-producing bacteria were increased in patients with NAFLD.
  • [1.17] 
    -The exercise group showed improvements in the clinical indices of oral environment. Salivary component analysis revealed significant reductions in LPS, and lactoferrin during the exercise regimen.
    - Diversity analysis of oral bacterial flora revealed higher alpha- and beta-diversity after the exercise regimen.
    - Analysis of the microbial composition revealed that the numbers of Campylobacter, Corynebacterium, Actinomyces , and Lautropia were significantly higher, and that of Prevotella was significantly lower.
  • [1.18] 
    - Some Bacteroides species have been reported to be protective against MAFLD

Common References