Cervical cancer ⇒ Cancer {40000149}

Record Keys
Definition:	Cervical cancer
Class:	Cancer

Details
Other Terms:	[ ]
Authoring date:	2020-09-06

Links
Wickipedia Merck Manual

Meta Information
ICD:	[ ]
Category:	Urologic, Oncologic
MedDra ID:	10062663
MedDra Level:	llt

Notes

- Mycoplasmatales correlates directly with the severity of lesions and are more abundant in the presence of higher-grade lesions, and less abundant for lower-grade lesions. (1)

- The bacteria could promote HPV infection directly or indirectly -- by causing chronic inflammation, which promotes HPV. (1)

Common References

[1.1] Comositional and functional differences between microbiota and cervical carcinogenesis as identified by shotgun metagenomic sequencing [2019] [80000960] [Cancers]
[1.2] Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity [2015] [80000375] [Scientific Reports]
[1.3] Altered diversity and composition of the gut microbiome in patients with cervical cancer [2019] [80000943] [AMB Express]
[1.4] Microbiota dysbiosis is associated with HPV-induced cervical carcinogenesis [2018] [80001005] [Oncology Letters]

Increased abundance of

‐ Alkaliphilus Cervical swabs ‎Human [1.1]
‐ Anaerococcus tetradius Vaginal swab ‎Human [1.2]
‐ Dorea Faeces ‎Human [1.3]
‐ Gardnerella vaginalis Cervical swabs ‎Human [1.4]
‐ Halomonas Faeces ‎Human [1.3]
‐ Morganella Faeces ‎Human [1.3]
‐ Mycoplasmatales ‎Deteriorative ‎Cervix ‎Human
‐ Peptostreptococcus anaerobius Vaginal swab ‎Human [1.2]
‐ Proteus Faeces ‎Human [1.3]
‐ Pseudothermotoga Cervical swabs ‎Human [1.1]
‐ Roseburia Faeces ‎Human [1.3]
‐ Ruminococcus Faeces ‎Human [1.3]
‐ Shewanella Faeces ‎Human [1.3]
‐ Sneathia sanguinegens Vaginal swab ‎Human [1.2]
‐ Succinivibrio Faeces ‎Human [1.3]
‐ Wolbachia Cervical swabs ‎Human [1.1]

Decreased abundance of

‐ Lactobacillus crispatus Cervical swabs ‎Human [1.4]
‐ Lactobacillus iners Cervical swabs ‎Human [1.4]
‐ Lactobacillus taiwanensis Cervical swabs ‎Human [1.4]
‐ Phascolarctobacterium Faeces ‎Human [1.3]
‐ Pseudoalteromonas Cervical swabs ‎Human [1.1]
‐ Psychrobacter Cervical swabs ‎Human [1.1]

References

(1) Cervical microbiome may promote high-grade precancerous lesions [Report] [2019]

Cervical cancer ⇒ Cancer {40000149}

Record Keys

Details

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Meta Information

Notes

Common References