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Disease ⇒ Glaucoma {40000528}

Record Keys


Type:
Disease
Parent:[  ]
Definition:
Glaucoma

Details


Initialisation date:
2021-09-04
Other Terms:[  ]

Meta Information


MedDra ID:[  ]
MedDra Level:[  ]
ICD:[  ]
Category:[  ]
Zone:[  ]
Mechanism:[  ]

Notes:


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Shared Reference Notes


  • [1.1
  • [1.2
  • [1.3
    - CD4+ T cells express integrin β7 in the gut—this is a protein encoded by the ITGB7 gene. - CD4+ T cells were reprogrammed in the gut in a way that allowed them to use integrin β7 to access the retina and attack retinal ganglion cells when transported through the blood. - test mice antibodies prevented the cells from interacting with a protein known as MAdCAM-1, which led to a reduction in inflammation in the eye and damage to the retina.

References Notes


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Common References