Disease ⇒ Enterotoxin entrocolitis {40000525} Record Keys Type:Disease Parent:[ ] Definition:Enterotoxin entrocolitis Details Initialisation date:[ ] Other Terms:[ ] Meta Information MedDra ID:[ ] MedDra Level:[ ] ICD:[ ] Category:[ ] Zone:[ ] Mechanism:[ ] Notes: [ ]Shared Reference Notes [1.1] - Multiple non-digestible oligosaccharides (NDOs), and short chain fatty acids (SCFA), as their metabolites produced by the gut microbiota, interact with enteropathogens and their toxins, which may result in the inhibition of the bacterial pathogenicity. - NDOs characterized by diverse structural characteristics, block the pathogenicity of EPB either directly, by inhibiting bacterial adherence and growth, or biofilm formation or indirectly, by promoting gut microbiota. - Apart from these abilities, NDOs and SCFA can interact with enterotoxins and reduce their cytotoxicity by their ability to mimic the structure of toxin receptors and thus inhibiting toxin adherence to host cells.References Notes[ ]
