Irritable bowel syndrome {40000135}
Definition: | Irritable bowel syndrome |
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Class: | [ ] |
Other Terms: | IBS |
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Authoring date: | 2020-09-06 |
ICD: | [ ] |
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Category: | Gastroenterologic |
MedDra ID: | 10023003 |
MedDra Level: | pt |
Notes
- Oral administration of Bifidobacterium infantis 35624 normalized sensitivity to colorectal distension in a rat model of post-inflammatory colonic hypersensitivity (1)
- The probiotic B. infantis 35624 reduced CRD-induced visceral pain behaviors in both rat strains. It significantly increased the threshold pressure of the first pain behavior and also reduced the total number pain behaviors during CRD (2)
- Purine metabolism is the novel host-microbial metabolic pathway in IBS (4)
Shared Notes
- [1.24]
- Bifidobacterium infantis seems to be effective in human studies with IBS patients by changing plasma proinflammatory to anti-inflammatory cytokine ratio. - [1.23]
- Mice colonized with IBS+A microbiota developed faster gastrointestinal transit and anxiety‐like behavior (longer step‐down latency) compared to mice with HC microbiota.
- Saccharomyces boulardii administration normalized gastrointestinal transit and anxiety‐like behavior in mice with IBS+A microbiota.
Step‐down latency correlated with colonic Trpv1 expression and was associated with altered microbiota profile and increased Indole‐3‐acetic acid (IAA) levels.
Common References
- [1.1] Structural alterations of faecal and mucosa-associated bacterial communities in irritable bowel syndrome [2012] [80000629] [Environmental Microbiology Reports]
- [1.2] Dysbiosis of fecal microbiota and high frequency of Citrobacter, Klebsiella spp., and Actinomycetes in patients with irritable bowel syndrome and gastroenteritis [2016] [80000589] [Gastroenterology and Hepatology]
- [1.3] An irritable bowel syndrome subtype defined by species-specific alterations in faecal microbiota [2012] [80000591] [Gut]
- [1.4] Molecular assessment of differences in the duodenal microbiome in subjects with irritable bowel syndrome [2015] [80000415] [Scand J Gastroenterol]
- [1.5] Gut microbiota dysbiosis in children with relapsing idiopathic nephrotic syndrome [2018] [80000692] [American Journal of Nephrology]
- [1.6] The fecal microbiota of irritable bowel syndrome patients differs significantly from that of healthy subjects [2007] [80001076] [Gastroenterology]
- [1.7] Intestinal fungal dysbiosis is associated with visceral hypersensitivity in patients with irritable bowel syndrome and rats [2017] [80001060] [Gastroenterology]
- [1.8] Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. [2011] [80000294] [Gastroenterology]
- [1.9] Fecal microbiota in patients with irritable bowel syndrome compared with healthy controls using real-time polymerase chain reaction: an evidence of dysbiosis. [2015] [80000236] [Digestive Diseases and Sciences]
- [1.10] Characteristic dysbiosis of gut microbiota of Chinese patients with diarrhea-predominant irritable bowel syndrome by an insight into the pan-microbiome [2019] [80001123] [Chinese Medical Journal]
- [1.11] Evidence of altered mucosa-associated and fecal microbiota composition in patients with irritable bowel syndrome [2020] [80001337] [Scientific Reports]
- [1.12] Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome [2011] [80000291] [Gastroenterology]
- [1.13] Fecal and Mucosa-associated intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome [2018] [80000864] [Digestive Diseases and Sciences]
- [1.14] Quantitative profiling of gut microbiota of children with diarrhea-predominant irritable bowel syndrom [2012] [80000293] [The American Journal of Gastroenterology]
- [1.15] Functional dysbiosis within the gut microbiota of patients with constipated-irritable bowel syndrome [2012] [80000623] [Alimentary Pharmacology and Therapeutics]
- [1.16] Mucosal microbiome profiles polygenic irritable bowel syndrome in Mestizo individuals [2020] [80001366] [Frontiers in Cellular and Infection Microbiology]
- [1.17] Fecal and mucosal microbiota profiling in irritable bowel syndrome and inflammatory bowel disease [2019] [80001146] [Frontiers in Microbiology]
- [1.18] Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome [2017] [80000467] [Microbiome]
- [1.19] Molecular characterization of the intestinal microbiota in patients with and without abdominal bloating [2016] [80000352] [American journal of physiology. Gastrointestinal and liver physiology]
- [1.20] Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome_DUBLICATE [2018] [80000965] [Science translational medicine]
- [1.21] Lower Bifidobacteria counts in both duodenal mucosa-associated and fecal microbiota in irritable bowel syndrome patients_DUBLICATE [2009] [80001228] [World journal of gastroenterology]
- [1.22] Analysis of the fecal microbiota of irritable bowel syndrome patients and healthy controls with real-time PCR [2005] [80000290] [American Journal of Gastroenterology]
- [1.23] Saccharomyces boulardii CNCM I‐745 modulates the microbiota–gut–brain axis in a humanized mouse model of Irritable Bowel Syndrome [2020] [Research] [80001673] [Neurogastroenterology & Motility]
- [1.24] The Microbiota and Gut-Brain Axis [2016] [Report] [80000021] [Journal of Mood Disorders]