Microbiome & Chronic Diseases

Evidence Based Medicine

Viral respiratory tract infection {40000358}

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Viral respiratory tract infection
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Shared Notes

  • [1.2
    - A healthy URT microbiota includes taxa such as Corynebacterium, Staphylococcus, Streptococcus, Fusobacterium, Moraxella, Prevotella, Rothia, and lactic acid bacteria.
    - theoretically, beneficial bacteria > prevent binding of respiratory viruses to host cells through broader blocking mechanisms, such as trapping viral particles by direct interaction with the virus or by physically blocking virus adhesion to host cells by occupying viral receptors.
    - Several metabolites of lactic acid bacteria display direct antiviral potential, such as d- and l-lactic acid that can reduce influenza A virus A/WSN/33 (H1N1).
    - A pediocin-like bacteriocin from E. faecium ST5Ha inhibits viral activity of herpes simplex virus type 1
    - Valinomycin, a non-ribosomal peptide produced by Streptomyces and the potentially beneficial respiratory commensal Rothia shows potent in vitro activity against RSV

Common References