Microbiome & Chronic Diseases

Evidence Based Medicine

COPD Exacerbation {40000343}

Record Keys
Definition:	COPD Exacerbation
Class:	[ ]

Details
Other Terms:	[ ]
Authoring date:	[ ]

Meta Information
ICD:	[ ]
Category:	[ ]
MedDra ID:	10010953
MedDra Level:	llt

Notes

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Common References

[1.1] Dynamic changes of gut and lung microorganisms during chronic obstructive pulmonary disease exacerbations [2020] [80001387] [The Kaohsiung Journal of Medical Sciences]
[1.2] Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study [2019] [80001100] [Respiratory Research]
[1.3] Exacerbation induces a microbiota shift in sputa of COPD patients [2018] [80000713] [PLOS ONE]

Increased abundance of

‐ Acinetobacter Sputum ‎Human [1.1]
‐ Haemophilus Sputum ‎Human [1.1, 1.2]
‐ Haemophilus influenzae Sputum ‎Human [1.3]
‐ Moraxella Sputum ‎Human [1.1, 1.2]
‐ Moraxella catarrhalis Sputum ‎Human [1.3]
‐ Proteobacteria Sputum ‎Human [1.1]
‐ Streptococcus pneumoniae Sputum ‎Human [1.3]

Decreased abundance of

‐ Actinomyces Sputum ‎Human [1.2]
‐ Bergeyella Sputum ‎Human [1.2]
‐ Campylobacter Sputum ‎Human [1.2]
‐ Capnocytophaga Sputum ‎Human [1.2]
‐ Firmicutes Sputum ‎Human [1.1]
‐ Gemella Sputum ‎Human [1.2]
‐ Lachnospiraceae Sputum ‎Human [1.2]
‐ Prevotella Sputum ‎Human [1.2]
‐ Ruminococcaceae Sputum ‎Human [1.1]
‐ Streptococcus Sputum ‎Human [1.1, 1.2]
‐ Subdoligranulum Sputum ‎Human [1.1]
‐ Treponema Sputum ‎Human [1.2]