Microbiome & Chronic Diseases

Evidence Based Medicine

Sun 28 November 2021 Sign in

COPD Exacerbation {40000343}

Record Keys
Definition:	COPD Exacerbation
Class:	[ ]

Details
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Initialisation date:	[ ]

Meta Information
ICD:	[ ]
Category:	[ ]
MedDra ID:	10010953
MedDra Level:	llt

Notes

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Shared Notes

[1.4]
- Proteobacteria, Actinobacteria, and Firmicutes > biosynthesis of palmitate, homocysteine, and urate > promote the development of COPD.

Common References

[1.1] Dynamic changes of gut and lung microorganisms during chronic obstructive pulmonary disease exacerbations [2020] [The Kaohsiung Journal of Medical Sciences] [Journal] [80001387]
[1.2] Exacerbation induces a microbiota shift in sputa of COPD patients [2018] [PLOS ONE] [Journal] [80000713]
[1.3] Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study [2019] [Respiratory Research] [Journal] [80001100]
[1.4] Microbiota Emergencies in the Diagnosis of Lung Diseases: A Meta-Analysis [2021] [Meta-Analysis] [Frontiers in Cellular and Infection Microbiology] [Journal] [80002102]

Increased abundance of

‐ Acinetobacter Sputum ‎Human [1.1]
‐ Haemophilus influenzae Sputum ‎Human [1.2]
‐ Haemophilus Sputum ‎Human [1.3]
‐ Moraxella catarrhalis Sputum ‎Human [1.2]
‐ Moraxella Sputum ‎Human [1.1]
‐ Proteobacteria Sputum ‎Human [1.1]
‐ Streptococcus pneumoniae Sputum ‎Human [1.2]

Decreased abundance of

‐ Actinomyces Sputum ‎Human [1.3]
‐ Bergeyella Sputum ‎Human [1.3]
‐ Campylobacter Sputum ‎Human [1.3]
‐ Capnocytophaga Sputum ‎Human [1.3]
‐ Firmicutes Sputum ‎Human [1.1]
‐ Gemella Sputum ‎Human [1.3]
‐ Lachnospiraceae Sputum ‎Human [1.3]
‐ Prevotella Sputum ‎Human [1.3]
‐ Ruminococcaceae Sputum ‎Human [1.1]
‐ Streptococcus Sputum ‎Human [1.1]
‐ Subdoligranulum Sputum ‎Human [1.1]
‐ Treponema Sputum ‎Human [1.3]

Related Factor

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Related Metabolome

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References

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