MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine

Non alcoholic steatohepatitis {40000296}

Record Keys


Definition:
Non alcoholic steatohepatitis
Class:[  ]

Details


Other Terms:
NASH
Authoring date:[  ]

Meta Information


ICD:[  ]
Category:[  ]
MedDra ID:
10053219
MedDra Level:
pt

Notes


[  ]

Shared Notes


  • [1.8
    - Following administration of a high-fructose, high-fat diet, mice that received the human NAFL microbiota (NAFLR) gained more weight and had a higher liver triglycerides level and higher plasma LDL cholesterol than mice that received the human healthy microbiota (HR).

    - Metabolomic analyses revealed that it was associated with lower and higher plasma levels of glycine and 3-Indolepropionic acid in NAFLR mice, respectively. Moreover, several bacterial genera and OTUs were identified as differently represented in the NAFLR and HR microbiota and therefore potentially responsible for the different phenotypes observed.

Common References