MetaBiom
Microbiome & Chronic Diseases

Evidence Based Medicine
Sign in

Allergy {40000209}

Record Keys


Definition:
Allergy
Class:[  ]

Details


Other Terms:[  ]
Initialisation date:[  ]

Meta Information


ICD:[  ]
Category:[  ]
MedDra ID:
10001738
MedDra Level:
llt

Notes


[  ]

Shared Notes


  • [1.4
    - Decreases in the bacterially fermented metabolites of glycans, SCFAs, have been associated with IgE-mediated food allergy, providing an example of how dietary-driven microbiota changes can influence human health and disease
  • [1.5
    - Cutibacterium > ferments hexoses > Embden–Meyerhof pathway > produce pyruvate > metabolized into propionate > reduce antigen presentation on dendritic cells as > GPR41-dependent modulation of hematopoiesis and affected allergic diseases in a mouse model


[Coverage other Diseases (Overlap > 0.25)]

DiseaseOverlapCommon increased OrganismCommon decreased Organism
Allergy 1.0000 7 (100%) : Bifidobacterium adolescentis | Blautia | Clostridium | Dorea | Faecalibacterium | Roseburia | Ruminococcus gnavus 7 (100%) : Bacteroides | Bifidobacterium bifidum | Coprococcus | Enterococcus | Lachnospira | Lactobacillus | Prevotella
Ulcerative Colitis 0.8571 6 (86%) : Blautia | Clostridium | Dorea | Faecalibacterium | Roseburia | Ruminococcus gnavus 6 (86%) : Bacteroides | Coprococcus | Enterococcus | Lachnospira | Lactobacillus | Prevotella
Obesity 0.7857 5 (71%) : Bifidobacterium adolescentis | Blautia | Clostridium | Faecalibacterium | Roseburia 6 (86%) : Bacteroides | Bifidobacterium bifidum | Coprococcus | Lachnospira | Lactobacillus | Prevotella
Crohn's disease 0.6429 3 (43%) : Blautia | Clostridium | Ruminococcus gnavus 6 (86%) : Bacteroides | Coprococcus | Enterococcus | Lachnospira | Lactobacillus | Prevotella
Autism 0.6429 4 (57%) : Clostridium | Dorea | Roseburia | Ruminococcus gnavus 5 (71%) : Bacteroides | Coprococcus | Enterococcus | Lactobacillus | Prevotella
Psoriasis 0.5714 4 (57%) : Blautia | Dorea | Faecalibacterium | Ruminococcus gnavus 4 (57%) : Bacteroides | Coprococcus | Lachnospira | Lactobacillus
Irritable bowel syndrome 0.5714 4 (57%) : Blautia | Dorea | Roseburia | Ruminococcus gnavus 4 (57%) : Bacteroides | Coprococcus | Lachnospira | Lactobacillus
Multiple Sclerosis 0.5000 4 (57%) : Blautia | Clostridium | Dorea | Faecalibacterium 3 (43%) : Bacteroides | Lachnospira | Prevotella
Schizophrenia 0.5000 5 (71%) : Bifidobacterium adolescentis | Blautia | Clostridium | Dorea | Ruminococcus gnavus 2 (29%) : Coprococcus | Enterococcus
Non-alcoholic fatty liver disease 0.5000 2 (29%) : Dorea | Roseburia 5 (71%) : Bacteroides | Bifidobacterium bifidum | Coprococcus | Lactobacillus | Prevotella
Parkinson's Disease 0.5000 3 (43%) : Blautia | Faecalibacterium | Roseburia 4 (57%) : Coprococcus | Lachnospira | Lactobacillus | Prevotella
Type 2 diabetes 0.4286 3 (43%) : Dorea | Roseburia | Ruminococcus gnavus 3 (43%) : Coprococcus | Lachnospira | Prevotella
Colorectal cancer 0.4286 1 (14%) : Roseburia 5 (71%) : Bacteroides | Coprococcus | Lachnospira | Lactobacillus | Prevotella
Chronic kidney disease 0.4286 1 (14%) : Ruminococcus gnavus 5 (71%) : Bacteroides | Coprococcus | Enterococcus | Lachnospira | Prevotella
Major depressive disorder 0.4286 2 (29%) : Blautia | Roseburia 4 (57%) : Bacteroides | Coprococcus | Lactobacillus | Prevotella
Hashimoto's thyroiditis 0.4286 3 (43%) : Blautia | Dorea | Roseburia 3 (43%) : Bacteroides | Lactobacillus | Prevotella
Clostridium difficile infection 0.4286 2 (29%) : Clostridium | Dorea 4 (57%) : Bacteroides | Coprococcus | Lachnospira | Prevotella
Type 1 diabetes 0.3571 2 (29%) : Blautia | Clostridium 3 (43%) : Lachnospira | Lactobacillus | Prevotella
Rheumatoid Arthritis 0.3571 2 (29%) : Clostridium | Faecalibacterium 3 (43%) : Bacteroides | Lachnospira | Prevotella
Sjögren syndrome 0.3571 2 (29%) : Blautia | Clostridium 3 (43%) : Bacteroides | Enterococcus | Prevotella
Asthma 0.3571 2 (29%) : Faecalibacterium | Roseburia 3 (43%) : Enterococcus | Lachnospira | Prevotella
Cirrhosis 0.3571 2 (29%) : Clostridium | Ruminococcus gnavus 3 (43%) : Bacteroides | Lachnospira | Prevotella
Ankylosing spondylitis 0.3571 3 (43%) : Blautia | Dorea | Faecalibacterium 2 (29%) : Enterococcus | Lachnospira
Primary sclerosing cholangitis-IBD 0.3571 2 (29%) : Clostridium | Roseburia 3 (43%) : Bacteroides | Lachnospira | Prevotella
Hepatocellular cancer 0.3571 3 (43%) : Clostridium | Dorea | Faecalibacterium 2 (29%) : Enterococcus | Lactobacillus
Generalized anxiety disorder 0.3571 1 (14%) : Ruminococcus gnavus 4 (57%) : Bacteroides | Coprococcus | Lachnospira | Prevotella
Atopic Dermatitis 0.2857 1 (14%) : Faecalibacterium 3 (43%) : Coprococcus | Enterococcus | Lactobacillus
Hypertension 0.2857 2 (29%) : Clostridium | Dorea 2 (29%) : Coprococcus | Enterococcus
Inflamatory bowel disease 0.2857 1 (14%) : Ruminococcus gnavus 3 (43%) : Bacteroides | Coprococcus | Prevotella
Pouchitis 0.2857 2 (29%) : Clostridium | Roseburia 2 (29%) : Bacteroides | Lactobacillus
Short Bowel Syndrome 0.2857 0 (0%) 4 (57%) : Bacteroides | Lachnospira | Lactobacillus | Prevotella
Cystic fibrosis 0.2857 2 (29%) : Blautia | Ruminococcus gnavus 2 (29%) : Bacteroides | Prevotella
Celiac Disease 0.2857 1 (14%) : Dorea 3 (43%) : Enterococcus | Lactobacillus | Prevotella
HIV infection 0.2857 0 (0%) 4 (57%) : Bacteroides | Coprococcus | Lachnospira | Prevotella
Coronary artery disease 0.2857 1 (14%) : Ruminococcus gnavus 3 (43%) : Bacteroides | Coprococcus | Lachnospira
Colon adenomas 0.2857 2 (29%) : Dorea | Faecalibacterium 2 (29%) : Bacteroides | Coprococcus
Infantile eczema 0.2857 2 (29%) : Faecalibacterium | Roseburia 2 (29%) : Lactobacillus | Prevotella
Kawasaki disease 0.2857 4 (57%) : Blautia | Clostridium | Faecalibacterium | Roseburia 0 (0%)
Non alcoholic steatohepatitis 0.2857 2 (29%) : Blautia | Dorea 2 (29%) : Bifidobacterium bifidum | Coprococcus
Chronic alcoholic pancreatitis 0.2857 1 (14%) : Clostridium 3 (43%) : Bacteroides | Lachnospira | Prevotella
Gastric carcinoma 0.2857 1 (14%) : Clostridium 3 (43%) : Bacteroides | Lachnospira | Prevotella
Thyroid carcinoma 0.2857 2 (29%) : Blautia | Roseburia 2 (29%) : Bacteroides | Prevotella

[Coverage Factors (Overlap > 0.10)]

FactorOverlapCommon increased OrganismCommon decreased Organism
Consumption of Coffee 0.2143 3 (43%) : Blautia | Faecalibacterium | Roseburia 0 (0%)
Heat Stress 0.2143 1 (14%) : Clostridium 2 (29%) : Bacteroides | Lactobacillus
Chemotherapy treatment 0.1429 0 (0%) 2 (29%) : Bacteroides | Coprococcus
High Socio-economic status 0.1429 1 (14%) : Faecalibacterium 1 (14%) : Bacteroides
High Water drinking 0.1429 1 (14%) : Dorea 1 (14%) : Bacteroides