Atopy {40000206}
| Definition: | Atopy |
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| Class: | [ ] |
| Other Terms: | [ ] |
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| Initialisation date: | [ ] |
| ICD: | [ ] |
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| Category: | [ ] |
| MedDra ID: | 10003645 |
| MedDra Level: | pt |
Notes
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Shared Notes
- [1.3]
- Newborns who develop immunoglobulin E (IgE)-mediated allergic sensitization (atopy) by 1 year of age have a less-diverse gut metabolome at birth. - [1.4]
- There is an expansion of Candida sp. and Rhodotorula sp. in stool samples from US infants that later developed atopy. - [1.2]
- Early CMV infection > increased beta and decreased alpha diversity of the gut microbiota > persistent allergic sensitization at age 5 years
Common References
- [1.1] Unbalance of intestinal microbiota in atopic children [2012] [BioMed Central] [Journal] [80000322]
- [1.2] Early‐life cytomegalovirus infection is associated with gut microbiota perturbations and increased risk of atopy [2021] [Study] [Pediatric Allergy and Immunology] [Journal] [80002099]
- [1.3] A rich meconium metabolome in human infants is associated with early-life gut microbiota composition and reduced allergic sensitization [2021] [Research] [Cell Reports Medicine] [Journal] [80001790]
- [1.4] Intestinal fungi are causally implicated in microbiome assembly and immune development in mice [2020] [Review] [Nature communications] [Journal] [80001855]